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. 2022 Nov 8;11(11):1632. doi: 10.3390/biology11111632

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Functional association network for identified secreted factors released by SF-treated BMSCs. Using the online tool STRING, protein-protein interaction levels for 125 proteins of the BMSCs secretome were mined. The blue connections are for proteins with known interactions based on curated databases; violet connections for proteins with experimentally determined interactions. Empty nodes, proteins of unknown 3D structure; filled nodes, known or predicted 3D structure. Growth factors, insulin, IL6 and extracellular matrix related factors are shown.