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. 2022 Nov 8;11(11):1632. doi: 10.3390/biology11111632

Figure 6.

Figure 6

Comparison of EV-miRNA expression profiles between SF-treated BMSCs under study. (A), heat map of hierarchical clustering analysis of the normalized CRT values of detected miRNAs with sample clustering tree at the top. The color scale reflects the absolute expression levels: red shades = high expression levels (low CRT values) and blue shades = low expression levels (high CRT values). B1, B2 and B3 stands for BMSC donors 1, 2 and 3. (B), principal component analysis of the normalized CRT values of detected miRNAs. X and Y axis show principal component 1 and principal component 2 that explain 55% and 45% of the total variance. B1, B2 and B3 stands for BMSC donors 1, 2 and 3.