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. 2022 Nov 8;11(11):1632. doi: 10.3390/biology11111632

Table 2.

Most abundant (>1000 pg/million cells) SF-treated BMSCs factors.

pg/Million BMSCs
TYPE FACTOR B1 B2 B3 MEAN SD FUNCTION
GF IGFBP4 109,869 131,569 124,587 122,009 9045 Insulin-like growth factor-binding protein 4
GF IGFBP3 84,091 117,198 102,025 101,105 13,532 Insulin-like growth factor-binding protein 3
GF TGFB1 39,339 32,615 30,189 34,048 3870 Transforming growth factor beta-1
INF TIMP2 22,096 28,331 30,462 26,963 3550 Metalloproteinase inhibitor 2
CHE IFNL1 19,399 20,613 22,381 20,798 1225 Interferon lambda-1
CHE IL9 1770 24,217 16,270 14,086 9293 Interleukin-9
INF TIMP1 12,116 14,563 14,503 13,727 1140 Metalloproteinase inhibitor 1
GF BMP4 7872 10,892 20,075 12,946 5190 Bone morphogenetic protein 4
CYT SERPINE1 10,110 14,584 13,253 12,649 1876 Plasminogen activator inhibitor 1
GF IGFBP2 6439 14,130 10,661 10,410 3145 Insulin-like growth factor-binding protein 2
GF VEGFA 7794 12,442 10,732 10,323 1919 Vascular endothelial growth factor A
CHE PF4 9652 10,111 8745 9503 567 Platelet factor 4
GF IGFBP6 6466 10,314 9509 8763 1657 Insulin-like growth factor-binding protein 6
CHE MIF 3604 4526 4973 4368 570 Macrophage migration inhibitory factor
REC VCAM1 4131 5719 2852 4234 1173 Vascular cell adhesion protein 1
CYT INHBA 4344 4350 3770 4155 272 Inhibin beta A chain
CHE XCL1 2921 4047 5177 4048 921 Lymphotactin
CHE CCL27 4283 2370 3979 3544 840 C-C motif chemokine 27
CHE CXCL16 2374 3787 3932 3364 702 C-X-C motif chemokine 16
INF TNFRSF1A 2640 3403 3410 3151 361 Tumor necrosis factor receptor superfamily member 1A
CHE MST1 3356 1822 2150 2443 659 Hepatocyte growth factor-like protein
CHE CCL26 2212 932 4108 2417 1305 C-C motif chemokine 26
CHE CCL21 2552 3078 1594 2408 614 C-C motif chemokine 21
CHE CXCL11 2165 3168 1466 2266 698 C-X-C motif chemokine 11
REC PLAUR 1515 2482 1641 1879 429 Urokinase plasminogen activator surface receptor
CYT ANGPT1 1553 2005 1837 1798 187 Angiopoietin-1
GF BMP7 2239 327 1766 1444 813 Bone morphogenetic protein 7
CYT IL6ST 1239 1842 1090 1390 325 Interleukin-6 receptor subunit beta
GF HGF 1058 1462 1443 1321 186 Hepatocyte growth factor
GF FGF4 1536 1484 729 1250 369 Fibroblast growth factor 4
CYT ANG 971 1427 1301 1233 193 Angiogenin
REC ALCAM 956 1209 1239 1135 127 CD166 antigen
CYT FST 690 1260 1284 1078 274 Follistatin
CYT CTSS 808 1256 1150 1071 191 Cathepsin S
GF KDR 1078 887 1102 1022 96 Vascular endothelial growth factor receptor 2

CHE: Chemokine; CYT: Cytokine; GF: Growth factor; INF: Inflammation; REC: Receptor. B1, B2 and B3 stands for BMSC donors 1, 2 and 3.