Skip to main content
. 2022 Oct 29;10(11):2754. doi: 10.3390/biomedicines10112754

Figure 3.

Figure 3

(a) Antioxidant effects of HDL and LRP-1 and normal endothelial function; (b) impaired antioxidant mechanisms with consequential oxidative stress, inflammation and endothelial dysfunction in OSA. ABCA1—ATP-binding cassette transporter A1; ABCG1—ATP-binding cassette transporter G1; CD36—cluster determinant 36; CM—chylomicron; eNOS—endothelial nitric oxide synthase; HDL—high-density lipoprotein; IH—intermittent hypoxia; IL—interleukin; LDL—low-density lipoprotein; MMP—matrix metalloproteinase; NO—nitric oxide; oxLDL—oxidised-LDL; RCT—reverse cholesterol transport; ROS—reactive oxygen species; sLRP-1—soluble LDL receptor-related protein 1; Sr-A—macrophage scavenger receptor; SR-BI—scavenger receptor class B type I; VLDL—very-low-density lipoprotein. For description and references, please see the text.