Table 1.
Author, Month, Year | Study Design | Location Country | Age, Gender | Total Eyes | Diagnosis | COVID Status | Biochemistry | Comorbidity |
---|---|---|---|---|---|---|---|---|
Marinho PM et al [14], May, 2020 |
Case series | Brazil | Range 25–70 | 11 | Cotton wool spot and retinal microhemorrhages (n 4) | RT-PCR+ (n 9) Antibody+ (n 2) |
NA | NA |
Invernizzi A, et al [16], Oct, 2020 |
Case series | Italy | 50 (range 23–82) | 54 | Cotton wool spot (7.4%) Retinal hemorrhages (9.25%) Dilated veins (11.1%) Tortuous veins (12.9%) |
RT-PCR+ | PT (ratio) 1.19, PTT (ratio) 1.16 Fibrinogen (mg/dL) 550.2 CRP (mg/L) 26.2 Ferritin (mg/L) 662 LDH (U/L) 270.9 |
Hypertension, diabetes, dyslipidemia, stroke |
Aydemir E, et al [18], July, 2021 |
Case control series | Turkey | Mean 38 | 46 cases | Dilated arteries and veins | RT-PCR+ | NA | NA |
Pereira LA, et al [19], May 2020 |
Case series | Brazil | Median 62.5 | 18 | Cotton wool spot (16.7%) Retinal flame-shaped hemorrhages (22.2%) |
RT-PCR+ ICU (94.4%) |
NA | Hypertension, diabetes |
RT-PCR: real time polymerase chain reaction; IUC: intensive unit care; NA: not applicable; CRP: C-reactive protein; LDH: lactate dehydrogenase.