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. 2022 Nov 20;9(11):717. doi: 10.3390/bioengineering9110717

Table 2.

Overview of the characteristics reported in the studies included by Lalu et al. in their meta-analysis of pre-clinical trials with mesenchymal stem cells (MSCs) for ischemic stroke.

Characteristics Possible Variants Number of Studies
Stroke model permanent 34
transient 34
two arms 4
Animal species rat 61
mouse 9
dog (Beagle) 1
monkey (Macaca fascicularis) 1
Type of MSCs delivered bone marrow-derived MSCs 62
adipose tissue-derived MSCs 2
umbilical cord- or placenta-derived MSCs 8
Delivery route intracerebral 37
intravenous 26
intra-arterial 4
intranasal 1
mixed delivery routes 4