FIG. 2.

Survival of BALB/c mice treated with anti-mouse CD40 ligand monoclonal antibodies following oral challenge with Salmonella. Groups of mice (12 per group) were treated i.p. with either 0.5 mg of anti-mouse CD40 ligand monoclonal antibody (Anti CD40L) or 0.5 mg of nonspecific rat IgG (Rat Ig) according to the regimen described in Materials and Methods both prior to and following oral challenge with 10⁶ Salmonella bacteria. Results are presented as the percent survival following oral challenge with Salmonella.