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Parameters for the simulation study.
| Parameter | Value |
|---|---|
| Number of UOs | 4 |
| Parameters per UO | 5 |
| CQA type | Impurity |
| hDoE start runs | 6 |
| Noise/std ratio for residual error | 0.5 (0.9 in study D) |
| Number of runs recommended per cycle | 1 |
| Variable selection method | Bi-directional stepwise |
| p-value threshold for including effect | 0.25 |
| p-values threshold for excluding effect | 0.05 |
