Cerebral cortical functional connectivity and centrality undergo large shifts from rest to locomotion and return to rest. (A) Significant changes in correlations between nodes during treadmill locomotion across sequential behavior periods (α < 0.05, with false discovery rate correction). The nodes and changes in functional connectivity are superimposed on the cortical surface. Significant increases shown in red (top) and decreases in blue (bottom). Directly above, the grey bracket indicates the adjacent behavior periods being compared (i–vi). The size of each node reflects the magnitude of significant increases or decreases, respectively. (B) Significant change in eigenvector centrality across the sequential behavior periods as in (A). Size of circles denote the magnitude of the change, while circle color is the direction of significant change (red = increase, blue = decrease, black = not significant; α < 0.05, with false discovery rate). Modified from [61] with permission.