Table 3.
Patient demographics and clinical characteristics.
| Characteristics | Total | HPV+ | HPV− | |
|---|---|---|---|---|
| No. (%) | No. (%) | No. (%) | ||
| No. of patients | 97 (100%) | 45 (46%) | 52 (54%) | |
| Age | Mean age | 57.23 | 57.98 | 56.58 |
| (years) | Median age | 58 | 59 | 56 |
| Gender | female | 19 (20%) | 10 (22%) | 9 (17%) |
| male | 78 (80%) | 35 (78%) | 43 (83%) | |
| Tumor location | oropharynx | 83 (86%) | 45 (100%) | 38 (73%) |
| oral cavity | 14 (14%) | 0 (0%) | 14 (27%) | |
| Education a | >12 years | 33 (34%) | 18 (41%) | 15 (29%) |
| ≤12 years | 63 (66%) | 26 (59%) | 37 (71%) | |
| Smoking | never | 19 (20%) | 15 (33%) | 4 (8%) |
| past | 32 (33%) | 19 (42%) | 13 (25%) | |
| current | 46 (47%) | 11 (25%) | 35 (67%) | |
| Alcohol | never | 20 (21%) | 12 (27%) | 8 (15%) |
| consumption | past | 13 (13%) | 7 (16%) | 6 (12%) |
| current | 64 (66%) | 26 (57%) | 38 (73%) | |
| No. of sex partners | >7 | 41 (46%) | 15 (35%) | 26 (55%) |
| ≤6 | 49 (54%) | 28 (65%) | 21 (45%) | |
| Tumor size | T1 | 17 (18%) | 7 (16%) | 10 (19%) |
| (pT) | T2 | 61 (63%) | 27 (60%) | 34 (65%) |
| T3 | 13 (13%) | 9 (20%) | 4 (8%) | |
| T4 | 6 (6%) | 2 (4%) | 4 (8%) | |
| Nodal status | N0 | 31 (32%) | 9 (20%) | 22 (42%) |
| (pN) | N1 | 16 (16.5%) | 5 (11%) | 11 (21%) |
| N2 | 47 (48.5%) | 28 (62%) | 19 (37%) | |
| N3 | 3 (3%) | 3 (7%) | 0 (0%) | |
| Metastasis | 0 | 97 (100%) | 45 (100%) | 52 (100%) |
| (M) | 1 | 0 (0%) | 0 (0%) | 0 (0%) |
| Tumor stage | I | 5 (5%) | 1 (2%) | 4 (8%) |
| (S) | II | 24 (25%) | 6 (13%) | 18 (35%) |
| III | 16 (16%) | 7 (16%) | 9 (17%) | |
| IV | 52 (54%) | 31 (69%) | 21 (40%) | |
| Tumor grade | 1 | 14 (14%) | 3 (7%) | 11 (21%) |
| 2 | 57 (59%) | 25 (55%) | 32 (62%) | |
| 3 | 26 (27%) | 17 (38%) | 9 (17%) | |
| Relapse | no | 82 (85%) | 41 (91%) | 41 (79%) |
| yes | 15 (15%) | 4 (9%) | 11 (21%) |
a For one patient, data were not available.