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. 2022 Oct 25;10(11):2700. doi: 10.3390/biomedicines10112700

Table 7.

Clinical trials targeting IL-22 in AD.

Target Molecule Clin Trial Gov Type of Study Status
IL-22
Anti-IL-22 antibody
Fezakinumab (ILV-094)
NCT01941537 Phase II Completed
IL-22R1
Anti-IL-22R1 antibody
LEO 138559
NCT04922021 Phase II for AD Active, not recruiting
Anti-IL-22R1 antibody
LEO 138559
NCT03514511 Phase I Completed
Anti-IL-22R1 antibody
LEO 138559
NCT05099133 Phase I Completed
Anti-IL-22R1 antibody
LEO 138559
NCT05470114 Phase II Recruiting