Table 15.
Clinical trials targeting IL-5 in AD.
| Target Molecule | Clin Trial Gov | Type of Study | Status |
|---|---|---|---|
| IL-5 | |||
| Anti-IL-5 monoclonal antibody mepolizumab |
NCT03055195 | Phase II for AD | Terminated (This study reached the pre-determined futility criteria following interim analysis. No safety concerns were noted) |
| IL-5Rα | |||
| Benralizumab Monoclonal antibody anti-IL-5Rα |
NCT03563066 | Phase II for AD | Completed |
| Benralizumab Monoclonal antibody anti-IL-5Rα |
NCT04605094 | Phase II for AD | Active, not recruiting |