ABCB1 |
ATP binding cassette subfamily B member 1 |
anti-CTLA4 |
Anti-cytotoxic T lymphocytes A4 antibodies |
Asp |
Aspartic acid |
CD8 |
Cluster of differentiation 8 |
CHK1 |
Checkpoint kinase 1 |
CLL |
Chronic lymphocytic leukemia |
CTLA |
Cytotoxic T-lymphocyte-associated protein gene |
Cys |
Cysteine |
DNA |
Deoxyribonucleic acid |
DNMT1 |
DNA (cytosine-5)-methyltransferase 1 |
DUBs |
Deubiquitinases |
Foxp3 |
Forkhead box P3 |
Gly |
Glycine |
HAUSP |
Herpes virus-associated protease |
HDAC |
Histone deacetylase 1 |
His |
Histidine |
IFN-γ |
Interferon-gamma |
IL |
Interleukin |
mAb |
Monoclonal antibodies |
MAPK |
Mitogen-activated protein kinase |
MDM2 |
Mouse double minute 2 homolog |
MGA |
MAX dimerization protein |
MINDY |
Motif interacting with ubiquitin-containing novel deubiquitinase family proteases |
MJD |
Machado–Joseph (Josephin) domain containing proteases |
MM |
Multiple myeloma |
NOXA |
Phorbol-12-myristate-13-acetate-induced protein 1 |
OTU |
Ovarian tumor proteases |
PD-1 |
Programmed cell death protein |
PD-L1 |
Programmed death-ligand 1 |
PDX |
Patient-derived xenografts |
PHIP1 |
Pleckstrin homology domain interacting protein |
PP2A |
Protein phosphatase 2A |
PROTAC |
Proteolysis targeting chimera |
PTM |
Posttranslational modification |
Raf-1 |
RAF proto-oncogene serine/threonine-protein kinase |
RNA |
Ribonucleic acid |
siRNA |
Small interfering ribonucleic acid |
TAMs |
Tumor-associated macrophages |
Teffs |
Effector T cells |
Tip60 |
Tat-Interactive Protein |
TME |
Tumor microenvironment |
TNBC |
Triple-negative breast cancer |
TNF-α |
Tumor necrosis factor-alpha |
TP53 |
Tumor protein p53 |
TRAF |
Tumor necrosis factor Receptor-Associated Factor |
Tregs |
Regulatory T cells |
Ub |
Ubiquitin |
UBL |
Ubiquitin-like domain |
UCH |
Ubiquitin carboxyl-terminal hydrolases |
UPS |
Ubiquitin-proteasome system |
USP |
Ubiquitin-specific protease |
USP7 |
Ubiquitin-specific protease 7 |
WT |
Wild type |
XIAP |
X-linked inhibitor of apoptosis protein |