Table 2.

Supporting evidence for the dynamic criteria of cut-off margin lengths according to tumor dimension in oral cancer.

Tumor Variables (Reference No.)	Number of Patients	Findings	p -Value		p -Value
Tumor status [55]	90	Microscopic infiltration
T1–2		0.96 ± 0.54 mm
T3–4		1.76 ± 1.20 mm	<0.001
Depth of invasion [57]	100	PNI		LVI
<4 mm		2%		10%
≥4 mm		38%	<0.01	28%	0.02
MTR in deep resection [58]	501	Two-year locoregional control rate
>0.3		94%
≤0.3		87%
Log MTR [59]	302	Five-year disease-specific survival
>33%		HR 1
≤33%		HR 2.48	<0.001

HR: hazard ratio; LVI: lymphovascular invasion; MTR: margin to thickness ratio; PNI: perineural invasion.