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. 2022 Nov 11;14(22):5549. doi: 10.3390/cancers14225549

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Representative images of [⁶⁸Ga]Ga-Pentixafor PET/MRI in the HCT116 CAM-xenograft model. Upper row: baseline scan after i.v. injection of 7.19 MBq [⁶⁸Ga]Ga-Pentixafor (0.79 nmol peptide) on EDD16. Lower row: blocking (315 µg AMD3100/egg) of [⁶⁸Ga]Ga-Pentixafor uptake (18.32 MBq, 3.12 nmol peptide) in the same subject on the following day (EDD17). Left: T2-weighted TurboRARE images, right: [⁶⁸Ga]Ga-Pentixafor PET 60 min p.i., middle: fused PET/MRI (axial planes are shown). HCT116 CAM-xenografts are marked with a yellow arrow.