Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 15;11(22):3619. doi: 10.3390/cells11223619

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Differential gene expression patterns in individuals with MS and controls, assessed by RNAseq analysis. The graphs represent a heatmap (A) and a volcano plot (B) of differentially expressed genes (fold change > 1.5, p < 0.05) in MS and controls. Up-regulated genes in MS (red) and controls (blue) were indicated and ranked from highest to lowest fold change in MSLCL. For this analysis, a total of 20 LCL established from controls (coLCL) and 59 LCL from individuals with MS (MSLCL) were used. Human genome version GRCh38/hg38 was used for RNAseq read mapping. Fold changes and statistical significances were listed in the supplement (Supplementary Tables S3 and S4).