Table 2.

Correlation of high CDCA5 mRNA expression with mRNA expression of adhesion molecule, MMPs, proliferation, PI3K/AKT/mTOR pathway, apoptosis, and cyclin related genes.

Gene Names	METABRIC Cohort
	Correlation Value	p Value
Adhesion molecule genes
CDH1	−0.100	<0.001
CDH2	0.163	<0.001
	Proliferation gene
MKi-67	0.689	<0.001
MMPs related genes
MMP7	0.180	<0.001
MMP9	0.324	<0.001
MMP11	0.097	<0.001
MMP12	0.354	<0.001
MMP14	0.086	<0.001
MMP15	0.230	<0.001
MMP20	0.145	<0.001
MMP25	0.138	<0.001
	PI3K/AKT/mTOR pathway genes
PIK3CD	0.173	<0.001
AKT1	0.052	0.022
MTOR	0.125	<0.001
	Apoptosis gens
BAX	0.270	<0.001
MYC	0.173	<0.001
Cyclin related genes
CDKN2A	0.396	<0.001
CCNA1	0.236	<0.001
CCNA2	0.838	<0.001
CCNB1	0.614	<0.001
CCNB2	0.883	<0.001
CCND3	0.096	<0.001
CCNE1	0.680	<0.001
CCNE2	0.671	<0.001
CCNT1	0.128	<0.001
CDK1	0.726	<0.001
CDK2	0.572	<0.001
CDK4	0.442	<0.001
CDK5	0.191	<0.001
CDK6	0.221	<0.001

Significant correlations are in bold.