Table 1.

Contributions of CD36 expression in various type of cancer tissues.

Type of Cancer	Contribution of CD36	References
Acute myeloid leukaemia	Increases leukaemia burden and shorten survival in vivo	[34]
Breast cancer	Essential survival mechanism in HER2-positive breast cancer Activates expression of pro-proliferation and migration genes while inhibiting expression of apoptotic genes	[35]
		[36]
Cervical cancer	Promotes the epithelial–mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β Promotes cervical cancer cell growth and metastasis via up-regulating the Src/ERK pathway	[37]
		[38]
Colorectal cancer	Promotes metastasis by increasing MMP28 and decreasing e-cadherin expression Increases in cellular proliferation via upregulation of survivin in CRC cells	[39]
		[40]
Gastric cancer	Promotes peritoneal metastasis via fatty acid uptake	[41]
	Promotes metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway	[42]
Glioblastoma	Increases glioblastoma progression and tumour initiation in cancer-stem cells	[43]
Hepatocellular carcinoma	Promotes epithelial–mesenchymal transition, enhances migration and invasion	[44]
Oral squamous carcinoma	Initiates and promotes metastasis and worsens prognosis Promotes lymph node metastasis	[45]
		[46]
Ovarian cancer	Omental adipocytes reprogram tumour metabolism due to high exogenous fatty acid uptake	[47]
	Facilitates the proliferation and migration and lymph node metastasis	[48]
Pancreatic cancer	Mediates pancreatic cancer development and progression	[49]
Prostate cancer	Increases cancer cell proliferation and migration, and increase tumour burden in vivo	[50]