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. 2022 Nov 16;14(22):5625. doi: 10.3390/cancers14225625

Table 1.

Demographic and Preoperative Clinical Characteristics of Patients Undergoing Distal Pancreatectomy in NSQIP (2014–2019).

Open
(n = 2982)
Hand-assisted
(n = 741)
Total
Laparoscopic
(n = 1913)
p Value
Age (years) 0.374
<65 1520 (51.0 %) 397 (53.6%) 1021 (53.4%)
65–80 1302 (43.7%) 312 (42.1%) 794 (41.5%)
>80 160 (5.4%) 32 (4.3%) 98 (5.1%)
Female sex 1675 (56.2%) 413 (55.7%) 1166 (61.0%) 0.002
Race <0.001
White 2262 (75.9%) 578 (78.0%) 1326 (69.3%)
Black 272 (9.1%) 69 (9.3%) 158 (8.3%)
Asian 91 (3.1%) 22 (3.0%) 113 (5.9%)
Other 14 (0.5%) 3 (0.4%) 13 (0.7%)
Hispanic 130 (4.4%) 41 (5.5%) 95 (5.0%) 0.317
BMI (kg/m2, Median, IQR) 27.63
(24.17–31.78)
28.58 (24.79–33.3) 28.21 (24.27–32.6) <0.001
ASA Class <0.001
1 29 (1.0%) 10 (1.4%) 32 (1.7%)
2 829 (27.8%) 234 (31.6%) 662 (34.6%)
3 1984 (66.5%) 466 (62.9%) 1135 (59.3%)
4 136 (4.6%) 30 (4.1%) 82 (4.3%)
Diabetes Mellitus <0.001
No 2201 (73.8%) 566 (76.4%) 1515 (79.2%)
Non–Insulin–Dependent 337 (11.3%) 63 (8.5%) 123 (6.4%)
Insulin–Dependent 444 (14.9%) 112 (15.1%) 275 (14.4%)
Smoking 482 (16.2%) 103 (13.9%) 266 (13.9%) 0.061
Dyspnea 167 (5.6%) 41 (5.5%) 118 (6.2%) 0.674
COPD 121 (4.1%) 28 (3.8%) 91 (4.8%) 0.391
CHF 15 (0.5%) 7 (0.9%) 2 (0.1%) 0.008
Hypertension requiring medications 1484 (49.8%) 400 (54.0%) 926 (48.4%) 0.036
Steroids Use 115 (3.9%) 38 (5.1%) 74 (3.9%) 0.263
Weight loss ( ≥10%) 210 (7.0%) 38 (5.1%) 57 (3.0%) <0.001
Bleeding Disorder 113 (3.8%) 21 (2.8%) 45 (2.4%) 0.017
Preoperative Albumin (g/dL, Median, IQR) 4.1 (3.9–4.4) 4.1 (3.8–4.4) 4.2 (3.9–4.4) 0.003
Pathological
Diagnosis
<0.001
Adenocarcinoma 1198 (40.2%) 197 (26.6%) 354 (18.5%)
Neuroendocrine Tumor 516 (17.3%) 204 (27.5%) 567 (29.6%)
Pancreatitis 211 (7.1%) 25 (3.4%) 63 (3.3%)
Pancreatic Cyst 670 (22.5%) 224 (30.2%) 703 (36.6%)
Neoadjuvant Chemotherapy 407 (13.7%) 29 (3.9%) 60 (3.1%) <0.001
T Stage <0.001
Not Applicable 1121 (37.6%) 322 (43.5%) 967 (50.6%)
T1 373 (12.5%) 124 (16.7%) 302 (15.8%)
T2 550 (18.4%) 129 (17.4%) 331 (17.3%)
T3 813 (27.3%) 148 (20.0%) 275 (14.4%)
T4 36 (1.2%) 1 (0.1%) 5 (0.3%)
N Stage <0.001
Not Applicable 993 (33.3%) 272 (36.7%) 603 (31.5%)
N0 693 (23.2%) 110 (14.8%) 220 (11.5%)
N1 1121 (37.6%) 323 (43.6%) 970 (50.7%)
Wound Classification <0.001
Clean 433 (14.5%) 88 (11.9%) 362 (18.9%)
Clean–Contaminated 2346 (78.7%) 631 (85.2%) 1488 (77.8%)
Contaminated 187 (6.3%) 21 (2.8%) 59 (3.1%)
Dirty/Infected 16 (0.5%) 1 (0.1%) 4 (0.2%)
Soft Pancreas 859 (28.8%) 147 (19.8%) 443 (23.2%) <0.001

Abbreviations: NSQIP: American College of Surgeons National Surgical Quality Improvement; IQR: Interquartile Range; BMI: Body Mass Index; COPD: Chronic Obstructive Pulmonary Disease; CHF: Congestive Heart Failure. Kruskal–Wallis test was used for continuous variables and χ2 test for categorical variables.