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(A) Schematic illustration of the functional mechanism of the probe TPETH-2(CFTERDn). n = 2 or 3 for chymase sensing. Reprinted with permission from ref. [42]. Copyright 2016, American Chemical Society. (B) Chemical structure of the activatable probe HPQF and its working mechanism with furin (top), and the molecular design strategy of the negative control non-cleavable probe HPQN (bottom). Reprinted with permission from ref. [44]. Copyright 2018, American Chemical Society.
