Table 1.
Clinicopathological characteristics of 396 patients with UTUC.
| Age at RNU *, years | 68.0 (60.0–76.0) |
| Sex | |
| Female | 127 (32.07) |
| Male | 269 (67.93) |
| HTN | 236 (59.60) |
| DM | 87 (21.97) |
| CAOD | 46 (11.62) |
| COPD, asthma | 35 (8.84) |
| CVA | 26 (6.57) |
| CKD | 45 (11.36) |
| Smoking history | |
| Never smoked | 210 (53.03) |
| Ex- or current smoker | 186 (46.97) |
| Tumor location | |
| Renal pelvis | 220 (55.56) |
| Ureter | 176 (44.44) |
| Laterality | |
| Left | 198 (50.00) |
| Right | 198 (50.00) |
| Previous/concurrent bladder cancer | 81 (20.45) |
| Urine cytology | |
| Not done | 136 (34.34) |
| Negative | 140 (35.35) |
| Atypical cell | 69 (17.43) |
| Positive | 51 (12.88) |
| Type of URS | |
| Non-URS | 107 (27.02) |
| Rigid URS | 178 (44.95) |
| Flexible URS | 111 (28.03) |
| Ureteroscopic biopsy | 140 (35.35) |
| Surgical modality | |
| Open | 105 (26.52) |
| Laparoscope or robot | 291 (73.48) |
| Pathologic T stage | |
| pTa | 35 (8.84) |
| pT1 | 126 (31.82) |
| pT2 | 80 (20.20) |
| pT3–4 | 155 (39.14) |
| Tumor grade | |
| Low grade | 44 (11.11) |
| High grade | 352 (88.89) |
| Pathologic N stage | |
| pN0 | 47 (11.87) |
| pNx | 332 (83.84) |
| pN+ | 17 (4.29) |
| Tumor size | |
| <2 cm | 66 (16.67) |
| ≥2 cm | 330 (83.33) |
| Lymphovascular invasion | 89 (22.59) |
| Carcinoma in situ | 55 (13.89) |
| Adjuvant chemotherapy | 114 (28.79) |
UTUC, upper tract urothelial carcinoma; URS, ureteroscopy; RNU, radical nephroureterectomy; HTN, hypertension; DM, diabetes mellitus; CAOD, coronary artery obstructive disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; CKD, chronic kidney disease. Data are presented as n (%); * Age at RNU is presented as a median (interquartile range).