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. 2022 Nov 20;14(22):5698. doi: 10.3390/cancers14225698

Table 1.

Studies investigating pulmonary metastasectomy in ACC.

Study n (ACC PMs) Intervention Outcomes Ref.
Girelli et al.
(2017)
109 PM:
83.5% CR
16.5% IR
5-year OS: 66.8%
10-year OS: 40.5%
[134]
Park et al.
(2022)
18 PM:
100% CR
1-year DFS: 88.9%
3-year DFS: 38.9%
5-year DFS: 32.4%
8-year DFS: 0%
[135]
Locati et al.
(2005)
20 PM:
55% CR
45% IR
Median OS:
78 mo. (CR) vs. 52 mo. (IR)
Median PFS:
30 mo. (CR) vs. 15 mo. (IR)
[136]
Liu et al.
(1999)
16 PM:
81% CR
19% IR
5-year OS: 84% [137]
Mazer et al.
(1988)
13 PM 5-year OS: 63% [138]
AlShammari et al.
(2020)
11 PM 5-year OS: 100% [139]
Bobbio et al.
(2008)
9 PM Median OS: 72 mo. [140]
Winter et al.
(2008)
6 PM 5-year OS: 33.3%
Median OS: 43.5 mo.
[141]
Ishida et al.
(2020)
5 PM 5-year OS: 100% [50]
Lu et al.
(2019)
3 PM 2-year OS: 100%
5-year OS: 100%
[142]

Abbreviations: ACC, adenoid cystic carcinoma; CR, complete resection; DFI, disease-free interval; DFS, disease-free survival; HNC, head and neck cancer; IR, incomplete resection; mo., months; OS, overall survival; PFS, progression-free survival; PM, pulmonary metastasectomy.