Table 1.

Potential multi-omics base Genomics biomarkers in CRC.

Biomarker	Sample Type	Change	Application	References
CBX8, CD96	datasets	downregulated	diagnostic	[54]
MTUS1	tissue	downregulated	diagnostic and prognostic	[55]
SDC2, NDRG4	stool	upregulated	Screening	[56]
SOX21	stool	upregulated	diagnostic	[57]
BDNF, PTGS2, GSK3B and CTNNB1	tissue	upregulated	prognostic and diagnostic	[33]
HPGD	tissue	downregulated	prognostic and diagnostic	[33]
YWHAB, MCM4, and FBXO46	datasets	overexpress	prognostic	[58]
DPP72	datasets	lower expression	prognostic	[58]
SDC2, TFPI2	stool	hypermethylated	screening	[59]
SNORD15B, SNORA5C	tissue	upregulated	diagnostic and prognostic	[60]
GALR1	tissue	hypermethylation	screening	[61]
LRRC19	datasets	downregulated	prognosis	[62]
KRAS, BRAF, PIK3CA	tissue	mutation	detection	[63]