Table 1.
Characteristics of included studies.
| Author/Year | Type of Study | Country | N° Lung Cancer pts | Follow Up | Risk of COVID (HR, 95%CI) | Severe Disease | Mortality % | Quality | Bias (ROBINS) |
|---|---|---|---|---|---|---|---|---|---|
| Assad et al., 2020 [10] | Retrospective study | France | 42 | Median 25 days | NR | NR | ↑ | 6 | Low |
| Aveyard et al., 2021 [11] | Retrospective cohort study | UK | 60 | NR | NR | ↑ * | ↑ * | 5 | Low |
| Basse et al., 2020 [12] | Prospective study | France | 18 | 28 days | NR | NR | ↑ # | 6 | Low |
| Beltramo et al., 2020 [13] | Retrospective cohort study | France | 977 | NR | NR | = * | ↑ * | 5 | Low |
| Benderra et al., 2021 [14] | Retrospective cohort study | France | 85 | 30 days | NR | NR | ↑ * | 6 | Low |
| Bernard et al., 2021 [15] | Retrospective cohort study | France | 873 | NR | NR | NR | ↑ * | 5 | Low |
| Chen et al., 2022 [16] | Cohort study | USA | 10,346 | NR | NR | NR | ↑ * | 5 | Low |
| Dai et al., 2020 [17] | Retrospective multicenter study | China | 31 | 53 days | NR | ↑ | ↑ | 7 | Low |
| De Joode et al., 2022 [18] | Prospective cohort study | Netherland | 117 | NR | NR | NR | ↑ $ | 6 | Low |
| Farooque et al., 2021 [19] | Prospective study | Pakistan | 159 | At least 30 days | NR | NR | ↑ *$ | 6 | Moderate |
| Fernandes et al., 2021 [20] | Retrospective cross-sectional study | Brazil | 18 | NR | NR | NR | ↑ *$ | 5 | Low |
| Ferrari et al., 2022 [21] | Prospective study | Brazil | 16 | Median 61 days | NR | NR | ↑ # | 7 | Low |
| Garassino et al., 2020 [22] | Cross-sectional and longitudinal cohort study | International | 200 | Median 15 days (IQR 8–24) | NR | NR | ↑ ** | 6 | Low |
| Jee et al., 2020 [23] | Retrospective observational study | USA | 29 | NR | NR | ↑ * | NR | 5 | Low |
| Khusid et al., 2021 [24] | Retrospective cohort study | USA | 14 | NR | NR | = * | ↑ * | 5 | Low |
| Kim et al., 2022 [25] | Retrospective study | USA | 887 | At least 30 days | NR | ↑ * | ↑ * | 7 | Low |
| Lee et al., 2020 [26] | Prospective observational study | UK | 90 | Max 39 days | NR | NR | = | 7 | Low |
| Lièvre et al., 2020 [27] | Retro-prospective cohort study | France | 311 | Median 34 days | NR | ↑ * | ↑ *,° | 7 | Low |
| Nader Marta et al., 2021 [28] | Retrospective, single-institute cohort study | Brazil | 42 | NR | NR | NR | ↑ *$ | 6 | Low |
| Oh et al., 2021 [29] | Retrospective study | South Korea | 769 | NR | NR | NR | ↑ *$ | 6 | Low |
| Ozdemir et al., 2021 [30] | Retrospective study | Turkey | 157 | Median 50 days (min 1- max 74) | NR | NR | ↑ *$ | 7 | Low |
| Preda et al., 2022 [31] | Retrospective study | Romania | 66 | NR | NR | NR | Not significant | 6 | Low |
| Song et al., 2020 [32] | Retrospective multicenter study | China | 61 | NR | NR | NR | ↑ $ | 8 | Low |
| Varnai et al., 2022 [33] | Prospective cohort study | UK | 265 | NR | NR | NR | ↑ *$ | 5 | Low |
| Wang et al., 2020 [34] | Retrospective case-control study | USA | 140 | NR | ↑ * | NR | NR | 5 | Low |
| Wang et al., 2022 [35] | Retrospective cohort study | USA | 2849 | NR | ↑ | NR | NR | 6 | Low |
| Yang et al., 2021 [36] | Retrospective cohort study | South Korea | 362 | NR | ↑ * | ↑ * | ↑ * | 4 | Low |
| Yarza et al., 2020 [37] | Retro-prospective study | Spain | 17 | NR | NR | ↑ * | ↑ *$ | 6 | Low |
| Zorzi et al., 2021 [38] | Retrospective population-based study | Italy | 2256 | NR | = * | NR | ↑ *^ | 6 | Low |
* Multivariate analysis; ° compared with non-thoracic cancer; # compared to breast cancer; ^ compared to colorectal cancer; $ compared to other cancers; ** compared to small cell lung cancer, = similar, ↑ increased.