Table 2.
The surface proteins with high-expression and high-risk in various cancer types.
| Cancer | High-Expressed and High-Risk Membrane Proteins in Pan-Cancer | Total |
|---|---|---|
| BLCA | CHRNA1, DRD5, HCN2, LRP8, RAC3, SLC1A6 | 6 |
| BRCA | FIBCD1, MAFA, PCDHA1, RGS9BP, SEZ6, ULBP2 | 6 |
| CHOL | RAET1E, RTBDN, TMEM17 | 3 |
| COAD | ASPHD1, CCDC78, CLDN6, DLL3, ELFN1, GABRD, GJA3, GNGT1, GPC2, KREMEN2, LIME1, LRRN4, MC1R, PANX2, PCP2, S1PR5, SLC16A8, SLC6A1, SYT8, TMEM213, TRPV4, UNC5A | 22 |
| ESCA | OR2W6P | 1 |
| HNSC | AMIGO2, DCBLD1, DSCAM, EMR1, FRMD5, MCEMP1, OLR1, OR11H7, OR5M11, RTN4R, TMEM92 | 11 |
| KICH | ADAM2, CSPG5, GSDMC, KCNC1, LRRTM3, MELK, SIGLEC15, TMPRSS11D | 8 |
| KIRC | ADAM11, ADAM12, ADAM8, ADD2, AGER, AQP9, ARHGEF39, ASGR1, ASIC3, ATP1A3, BEST1, BEST4, BTNL10, C20orf141, C9orf172, CABP7, CACNA2D4, CACNB1, CATSPER1, CCDC78, CD72, CDHR4, CDK5R2, CEACAM4, CELSR3, CLEC12B, CLEC2B, CLEC2D, CNIH2, CNTNAP1, CPNE7, CYTH4, DEF6, DLK2, DOK3, DRD4, EFNA3, EMR1, ENO2, FAP, FCGR1B, FCGR1C, FCRL2, FCRL5, FFAR3, FMNL1, FPR2,GABRE, GAD2, GGT2, GNG13, GPC2, GPR171, GPR19, GPR45, GPR84, GPR97, GPRIN1, GRIK4, GRIN2D, GRM2, GRM4, GSDMB, IGFLR1, IGLC6, IGLC7, IGLJ1, IL20RB, IL31RA, JPH3, KCNIP2, KCNN4, KIAA1324, KLRC4, KREMEN2, LAT, LAT2, LILRA6, LSMEM1, LTB4R, LTB4R2, LY6H, MARCO, MB21D1, MC1R, MCEMP1, MELK, MICALL2, MILR1, MMP17, MUC12, MUC3A, NPFFR1, NPY4R, NTM, NTNG2, OPN4, OR11H7, OR13A1, OR2B6, OSCAR, OTOF, PAQR6, PARVG, PCDHGC5, PDE6C, PIK3R6, PILRB, PLB1, PLEKHN1, PLXDC1, PLXNB3, PRAME, PRKCG, PRR7, PRRT2, PSD2, PSTPIP1, PTPRN, RASL10A, RELT, RLTPR, RTP5, SCNN1D, SIGLEC16, SLAMF8, SLAMF9, SLC16A8, SLCO5A1, SMIM23, SPHK1, STAC3, STX1B, TBC1D3B, TBC1D3F, TBC1D3L, TMPRSS6, TNFRSF25, TNFSF14, TPBGL, TRABD2A, TRBV28, TREML1, TRPM2, TRPM8, TTYH1, ZGRF1, ZP1 | 148 |
| KIRP | ADAM18, ADD2, ASIC3, CALN1, CDH17, CHRNA5, DLL3, GABRD, GJB4, GPA33, GPR19, GPRIN1, HTR1D, HTR3A, IL20RB, KIAA0319, KREMEN2, MELK, MFSD2B, OTOF, PTPRN, RTBDN, TMPRSS15, TNFSF9, ZP1 | 25 |
| LIHC | ABCC5, ADAM22, ANKRD13B, ANKRD27, ARHGEF39, ATP8A2, BAIAP2L2, BFSP1, CACNA1S, CD109, CDH10, CDK5R1, CHRNA5, CLCN2, CLEC2L, CNTNAP1, CSMD1, CSPG5, CT83, DAGLA, DDN, DUSP15, EFCAB7, EFNA3, EFNA4, EFNA5EGF, ENTPD2, EPHA6, FAM171A2, FIBCD1, FLVCR1, GABRA3, GDPD2, GJD4, GLDN, GLP1R, GNG4, GNGT1, GPR156, GPRC5D, GPRIN1, GPSM2, GRIN2D, GRM4, GSDMC, IGSF3, KCNE5, KCNQ3, KCTD7, KISS1R, KITLG, LRP12, LRP4, LRP8, LYSMD4, MAGEE1, MAPT, MELK, MEP1A, OR52E6, OR8A1, OR8G3P, OSBPL3, P2RY4, PDE6A, PIK3R6, PLXNA1, PLXNA3, PRR7, PRSS42, PTK7, PTPRN, PVRL1, RACGAP1, RAET1E, RNF144A, ROBO1, SAPCD2, SEMA4F, SHISA7, SLC16A3, SLC22A6, SLC26A2, SLC26A6, SLC30A8, SLC36A1, SLC38A6, SLC47A2, SLC7A1, SOCS7, SRGAP2, STX1A, STXBP5L, TBC1D30, TMEM206, TMEM213, TMEM65, TMEM67, TMEM81, TNFRSF11A, TREM2, TYRO3, XKR3, ZP3 | 105 |
| LUAD | ABCC2, ALPI, BAIAP2L2, C20orf141, CDH17, CDK5R1, CLDN14, DSG3, ENTPD2, FERMT1, GDPD2, GJA3, GJB2, GJB3, GJB4, GPR37, GPR78, GPR87, GPRIN1, GRIK2, HCN2, HTR1D, IL20RB, KCNV1, KIAA1549L, LGR4, LY6K, LYPD3, MELK, MFI2, OR10J6P, OR1F1, PLEK2, PTPRH, RAET1L, RHCG, RHOV, S100P, SAPCD2, SLCO1B3, STYK1, TMPRSS11E, TRPA1, UNC5D | 44 |
| PRAD | GPC2, KISS1R, NECAB2, PCDHA2, PCDHA9, SLC17A4 | 6 |
| READ | ATP6V0A4 | 1 |
| STAD | ADAM12, CLDN9, HTR1F, KIAA1549L, MCEMP1, NOX4, OR10A5, OR6A2, SLC22A16, TREML4 | 10 |
| THCA | DRD5, EFNA2, LHFPL5, MAST1, MCEMP1, NKD2, OR1F1, PCDHA2, PCDHA5, RTBDN, SLAMF9 | 11 |
| UCEC | ADAM18, ALPK2, ATP1A3, CABP7, CAMKV, CDH18, CDK5R2, CELSR3, CLDN6, CLDN9, DLL3, DSG1, GAL, GNG3, GPR110, GPR158, GPR19, GRIN2B, HEPHL1, HRH3, HTR3A, HTR3E, HTR6, KCNK9, KCNQ3, KCNS1, KIAA1549L, KLRG2, LIPH, MAFA, MAL, MAST1, MEP1A, MUC17, MUC3A, NKAIN1, NKAIN4, NTSR1, OTOG, P2RY2, PLA2G4F, PTPRN, RAC3, SHISA9, SLC12A3, SLC16A10, SLCO4C1 | 47 |