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. 2022 Nov 21;11(22):3703. doi: 10.3390/cells11223703

Figure 5.

Figure 5

Male kidney status: (A) Kidneys isolated at day 70 after birth from WT and G9KO male mice under a control diet and inosine supplementation. The morphological changes observed in G9KO male animals are significantly higher than the morphological changes observed in female G9KO animals. (B) Inosine supplementation results in a higher reduction in kidney mass in KO compared to WT animals. (C) HE, F4/80 (macrophages), and CD3 (T cells) stainings of WT (+/+) and KO (−/−) animals exposed to inosine during fetal development. Scale bar: 25 µm size; ** p < 0.01, *** p < 0.001.