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. 2022 Nov 9;14(22):5494. doi: 10.3390/cancers14225494

Figure 2.

Figure 2

Mutations in GBM6 derivative PDX. (A) Venn diagram illustrating numbers of mutated genes in PDX derivatives treated with radiation therapy (m4066, m4063, m4052). (B) Numbers of mutated genes in PDX derivatives treated with a single cycle of TMZ (m4056, m4082, m4883, m4057). (C) Comparison of numbers of mutated genes in PDX derivatives treated with indicated combinations of RT and TMZ. (D) Illustration and comparison of the relative frequency of mutations affecting C and T sites in select GBM6 derivatives treated with the indicated combinations of RT and TMZ.