Skip to main content
. 2022 Nov 9;14(22):5494. doi: 10.3390/cancers14225494

Figure 3.

Figure 3

Mutations in GBM12 derivative PDX. (A) Venn diagram illustrating numbers of mutated genes in PDX derivatives treated with RT (m6159, m6161). (B) Numbers of mutated genes in PDX derivatives treated with a single cycle of TMZ (m2657, m2656) versus four cycles of TMZ (m4829, m4834). (C) Numbers of mutated genes in PDX derivatives treated with RT plus a single cycle of TMZ (m2671, m2685) versus RT and 2 cycles of TMZ (m2511). (D) Relative frequency of mutations affecting C and T sites in select GBM12 derivatives treated with indicated combinations of RT and TMZ.