Table 1.
TCGA LGGs | CRNDE Expression | CGGA LGGs | CRNDE Expression | ||||||
---|---|---|---|---|---|---|---|---|---|
Factor | Number | High | Low | p | Factor | Number | High | Low | p |
Total no. of patients | 456 | 201 | 255 | Total No. of patients | 512 | 344 | 168 | ||
Age (y) | Age (y) | ||||||||
<40 | 210 | 71 | 139 | <0.001 | <40 | 242 | 151 | 91 | 0.031 |
≥40 | 246 | 130 | 116 | ≥40 | 269 | 192 | 77 | ||
Sex | Sex | ||||||||
Male | 249 | 111 | 138 | 0.814 | Male | 296 | 205 | 91 | 0.243 |
Female | 207 | 90 | 117 | Female | 216 | 139 | 77 | ||
Grade | Grade | ||||||||
WHO II | 218 | 64 | 154 | <0.001 | WHO II | 237 | 141 | 96 | <0.001 |
WHO III | 238 | 137 | 101 | WHO III | 275 | 203 | 72 | ||
IDH | IDH | ||||||||
Mutant | 372 | 132 | 240 | <0.001 | Mutant | 387 | 246 | 141 | 0.002 |
Wildtype | 84 | 69 | 15 | Wildtype | 125 | 98 | 27 | ||
1p19q | 1p19q | ||||||||
Codel | 146 | 22 | 124 | <0.001 | Codel | 162 | 63 | 99 | <0.001 |
Noncodel | 310 | 179 | 131 | Noncodel | 350 | 281 | 69 |