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. 2022 Nov 10;14(22):5518. doi: 10.3390/cancers14225518

Figure 1.

Figure 1

Plasma levels of catecholamines in a cohort of BC patients. Systemic levels of NE (a) and EPI (b) CORT (c) in the BC patients (n = 72) versus healthy donors (n = 18). The circulating levels of NE (d), EPI (e) and CORT (f) at all stages of the disease were discriminated in relation to the healthy donors (n = 18 per stage). Additionally, the systemic levels of NE (g), EPI (h), and CORT (i) in the BC patients displaying no distant metastasis (M0; n = 51) versus the BC patients with distant metastasis (M1; n = 18) were also analyzed. BC patients with distant metastasis exhibiting bone metastasis only (56%) or multiple metastasis sites (44%), namely, in bone, liver, brain, lung, and skin are shown (j). The systemic levels of catecholamines, NE and EPI, and CORT were compared between BC patients displaying bone metastasis only versus multiple metastasis sites (k). p-value < 0.05 (*); <0.01 (**), <0.001 (***) was considered statistically significant.