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Workflow of this unsupervised analysis based on DCE-MRI radiomics features in BC patients. In this study, we took advantage of DCE-MRI techniques and calculated the voxel-based percentage enhancement (PE) and signal enhancement ratio (SER) maps for each patient. Two independent radiogenomics cohorts (n = 246) were collected to identify and validate the novel imaging subtypes. The clinical and biological associations of DCE-MRI subtypes were further investigated.
