FIG. 4.

Transmission electron photomicrographs of T84 cell monolayers infected for 6 h. (A) EAEC strain 042. The appearance of the cells is comparable to that in images previously published by Nataro et al. (25); i.e., the monolayer demonstrates adherent bacteria, loss of microvilli, ballooning of the apical cytoplasm, and subnuclear vacuolization. (B) The pet mutant strain JIF1. The effects induced by the pet mutant strain are similar to those observed for the wild-type strain (042). (C) Pet-treated T84 cells. The appearance of the cells is similar to that of uninfected T84 cells.