Table 1.
Summarized clinical characteristics of the 25,103 patients included in this study.
| ADC | SCC | ASC | SGC | SC | NSCLC, NOS | SCLC | LCNEC | Total | ||
|---|---|---|---|---|---|---|---|---|---|---|
| N-MAC | MAC | |||||||||
| Total, n (%) | 12,455 (49.6) | 421 (1.7) | 6655 (26.5) | 126 (0.5) | 785 (3.1) | 225 (0.9) | 1713 (6.8) | 2373 (9.5) | 350 (1.4) | 25,103 (100) |
| Age, median (IQR) | 61 (53–69) | 62 (54–70) | 66 (60–72) | 62 (55–68) | 59 (50–67) | 64 (54–70) | 65 (56–71) | 65 (58–70) | 65 (60–71) | 63 (56–70) |
| Sex, n (%) | ||||||||||
| Male | 6849 (55.0) | 196 (46.6) | 6162 (92.6) | 92 (73.0) | 399 (50.8) | 177 (78.7) | 1344 (78.5) | 2059 (86.8) | 310 (88.6) | 17,594 (70.1) |
| Female | 5606 (45.0) | 225 (53.4) | 493 (7.4) | 34 (27.0) | 386 (49.2) | 48 (21.3) | 369 (21.5) | 314 (13.2) | 40 (11.4) | 7515 (29.9) |
| Metastasis, n (%) | ||||||||||
| Absent | 7363 (59.1) | 363 (86.2) | 5212 (78.3) | 81 (64.3) | 643 (81.9) | 135 (60.0) | 821 (47.9) | 1145 (48.3) | 187 (53.4) | 15,950 (63.5) |
| Present | 5092 (40.9) | 58 (13.8) | 1443 (21.7) | 45 (35.7) | 142 (18.1) | 90 (40.0) | 892 (52.1) | 1228 (51.7) | 163 (46.6) | 9153 (36.5) |
| Number of organs with metastasis, n (%) | ||||||||||
| 1–3 | 4786 (94.0) | 56 (96.6) | 1384 (95.9) | 40 (88.9) | 127 (89.4) | 81 (90.0) | 824 (92.4) | 1163 (94.7) | 146 (89.6) | 8607 (94.0) |
| 4–6 | 301 (5.9) | 2 (3.4) | 59 (4.1) | 4 (8.9) | 13 (9.2) | 8 (8.9) | 64 (7.2) | 64 (5.2) | 17 (10.4) | 532 (5.8) |
| 7+ | 5 (0.1) | 0 (0) | 0 (0) | 1 (2.2) | 2 (1.4) | 1 (1.1) | 4 (0.4) | 1 (0.1) | 0 (0) | 14 (0.2) |
| History of another malignancy | ||||||||||
| No | 11,279 (90.6) | 347 (82.4) | 5936 (89.2) | 117 (92.9) | 662 (84.3) | 198 (88.0) | 1635 (95.4) | 2251 (94.9) | 308 (88.0) | 22,733 (90.6) |
| Yes | 1176 (9.4) | 74 (17.6) | 719 (10.8) | 9 (7.1) | 123 (15.7) | 27 (12.0) | 78 (4.6) | 122 (5.1) | 42 (12.0) | 2370 (9.4) |
ADC, adenocarcinoma; N-MAC, non-mucinous adenocarcinoma; MAC, mucinous adenocarcinoma; SCC, squamous cell carcinoma; ASC, adenosquamous carcinoma; SGC, salivary-gland type carcinoma; SC, sarcomatoid carcinoma; NSCLC, non-small cell lung cancer; NOS, not otherwise specified; SCLC, small cell lung cancer; LCNEC, large cell neuroendocrine carcinoma; IQR, interquartile range; LCa, lung cancer; Dx, diagnosis.