Table 1.
General characteristics of NAFLD and non-NAFLD adolescents.
| NAFLD Adolescents |
Non-NAFLD Adolescents | p Value | |
|---|---|---|---|
| Age | 15.19 ± 2.42 | 16.2 ± 2 | n.s |
| Height (SDS) | 0.22 (−0.14–0.68) | −0.65 (−0.95–0.18) | n.s |
| Weight (Kg) | 94.83 ± 21.85 | 63.93 ± 14.78 | <0.05 |
| BMI (kg/m2) | 35.31 ± 7.9 | 25.76 ± 6.28 | <0.05 |
| WC (cm) | 107.75 (95–112) | 76.5 (67–91) | <0.05 |
| WC/H | 0.63 ± 0.10 | 0.51 ± 0.09 | <0.05 |
| SBP (mmHg) | 130 (115–137.5) | 120 (105–125) | <0.05 |
| DBP (mmHg) | 81.25 ± 11.1 | 72.37 ± 9.77 | <0.05 |
| Total cholesterol (mg/dL) | 160.5 (147–179) | 138 (123–173.5) | n.s |
| LDL-cholesterol (mg/dL) | 92.27 ± 25.37 | 80 ± 23.75 | n.s |
| HDL-cholesterol (mg/dL) | 53 ± 11.09 | 55.33 ± 12.78 | n.s |
| Triglycerides (mg/dL) | 89.81 ± 63.56 | 67.14 ± 42.96 | n.s |
| AST (U/L) | 23.10 ± 11.78 | 18.57 ± 4.40 | n.s |
| ALT (U/L) | 27 (21–37.5) | 20.5 (18–25.5) | n.s |
| FSH (mUI/mL) | 6.84 (4.49–8.2) | 3.82 (3.24–6.96) | n.s |
| LH (mUI/mL) | 14.4 (6.92–16.9) | 6.84 (4.44–15) | n.s |
| Total Testosterone (ng/mL) | 0.45 ± 0.19 | 0.43 ± 0.24 | n.s |
| Free Testosterone (pg/mL) | 2.4 ± 0.78 | 2.08 ± 1.02 | n.s |
| DHEAS (ug/dL) | 308 ± 126.63 | 305.45 ± 150.38 | n.s |
| Δ4-androstenedione (ng/dL) | 1.75 ± 0.89 | 1.62 ± 0.73 | n.s |
| 17β-Estradiol | 37.25 (26.45–43.6) | 60.05 (37.75–90.85) | n.s |
| Insulin (microUI/mL) | 27 (12.6–35.2) | 10.5 (8.45–21.4) | <0.05 |
| HOMA-IR | 6.07 (2.61–7.3) | 2.12 (1.72–4.51) | <0.05 |
| SHBG (nmol/L) | 16.65 (13.25–20.65) | 37.95 (22.8–46.1) | <0.01 |
Data are expressed as mean ± SD when normally distributed, median (quartile) when not normally distributed. Differences in not normally distributed continuous variables were assessed by Mann–Whitney U test for comparison between the two groups. Differences in normally distributed continuous variables were assessed by unpaired t test. n.s: not statistically significant. BMI: body mass index; WC: waist circumference; WC/H: waist circumference/height; SBP: systolic blood pressure; DBP: diastolic blood pressure; ALT: alanine aminotransferase, AST: aspartate aminotransferase; FSH: follicle stimulating hormone; LH: luteinizing hormone; DHEAS: dehydroepiandrosterone sulfate; HOMA-IR: homeostatic model assessment of insulin resistance; SHBG: sex hormone binding globulin.