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. 2022 Nov 15;12(11):2798. doi: 10.3390/diagnostics12112798

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Density of hippocampal ripples before and during SWD. (a) Ripple density during the 120 s preictal period divided into three statistically different clusters. Blue and rose stripes highlight significant differences of Cluster 1 (4.7% from all SWDs, shown in blue) and Cluster 2 (8.4%, shown in rose) from Cluster 3 (86.9%, shown in green, all p’s < 0.0001, Bonferroni tests. (b) Ripple density during a 40 s period around the onset of SWDs divided into three statistically different clusters. Blue and rose stripes mark significant differences between Cluster 3 and Cluster 1 (blue) & Cluster 3 and Cluster 2 (rose) (all p’s <0.05 Bonferroni tests).