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. 2022 Nov 9;11(22):3569. doi: 10.3390/foods11223569

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Metabolic network analysis of Hep G2 cells treated with GNR-L for 12 h: (a) all significant changed metabolites, (b) carbohydrate-related metabolites, (c) phosphorylate-related metabolites, (d) amino acid-related metabolites, (e) fatty acid-related metabolites. (f) Pathway enrichment analysis of significantly changed metabolites. Significantly changed pathways based on enrichment and topology analysis are shown. The x-axis represents pathway enrichment, and the y-axis represents pathway impact. Large sizes and yellow colors represent major pathway enrichment and high pathway impact values, respectively.