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. 2022 Nov 3;44(11):5416–5426. doi: 10.3390/cimb44110367

Figure 5.

Figure 5

S. horneri inhibited LPS-induced astrocyte and microglia activation in brain hippocampus. C57BL/6 mice were randomly divided into four groups. The control group was challenged with the same amount of solvent i.p. (n = 5). The treatment group was administered LPS (1 mg/kg) and S. honeri (10 and 20 mg/kg), following in vivo study design. Brain sections were immunostained with anti-GFAP (Green) or anti-Iba-1 (Red) antibody as described in the Materials and Methods section (scale bar = 100 μm). The result is representative of three repeated independent experiments. Each bar indicates the mean ± SE of four independent experiments. ** p < 0.01, significantly different from LPS-treated group; ## p < 0.01, significantly different from LPS-untreated group.