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. 2022 Nov 21;44(11):5788–5801. doi: 10.3390/cimb44110393

Figure 4.

Figure 4

p65-NF-κB inhibition partially reversed metabolic imbalance by superabundant RIP140. (A) ARPE-19 cells were infected with Ad-RIP140 (MOI 60, 48 h), simultaneously with p65 siRNA or Bay 11-7082 (10μM, 24 h) treatment. (A) Nuclear protein levels of NF-κB were assayed by Western blot. (B) Protein levels and (C) mRNA levels of PPAR-γ, (D) secretion levels of TNF-α, IL-β, and IL-6, (E) ATP production, (F) glycogen accumulation were performed as described in Section 2. *** p < 0.001 vs. Ad-GFP group. ### p < 0.001 vs. Ad-RIP140 group.