PSMA PET-CT scan showing normal distribution of PSMA-11. 60 yr old M—Gleason 6 prostate cancer on active surveillance for past 2 years; PSA 7.2; MR imaging—low grade changes PIRADS 2. PSMA PET-CT: 68Ga-PSMA - 204 MBq; uptake 52 min; BMI = 29.7; Wt 90 Kg; coronal PET and corresponding CT slices (soft tissue windows) from left to right. (a)—physiological uptake in lacrimal, submandibular salivary glands, parotid glands, retropharyngeal soft tissue, liver, bowel, part of spleen and pooling of tracer in bladder; mild reactive tracer uptake in groin and axillary nodes. (b)—physiological uptake in head and neck; reactive uptake axillary nodes; focal uptake in apex of prostate gland anterior below the bladder SUV = 9.1; marked uptake/excretion of tracer in both kidneys.