FIG. 3.

Space-filling three-dimensional molecular models of the calculated (MMC) lowest-energy states of the core oligosaccharide from galE mutants of L3 (a), L4 (b), and L8-dephosphorylated (c). The Kdo moiety indicated in gray is substituted at the O-5 position by the heptose disaccharide inner core unit (red); HepI provides the point via a glucose residue (dark green) for extension to give α-chain epitopes, while HepII is substituted by an N-acetylglucosamine residue (lighter green) at O-2. PEtn (brown) is shown in O-3 position in the L3 immunotype and O-6 in the L4 immunotype.