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. 2022 Oct 29;13(11):1975. doi: 10.3390/genes13111975

Table 2.

Summary statistics of the top SNPs associated with changes in body composition.

Gene/Near Gene SNP Chromo-some Allele 1/
Allele 2
MAF FM Change, % FFM Change, %
beta p beta p
ACSL1 rs116143768 4 T/C 0.0158 −27.55 1.18 × 10−9 * 6.91 2.35 × 10−6
PTPRZ1 rs79300430 7 G/T 0.0082 −34.91 6.14 × 10−8 7.32 4.19 × 10−4
KANK1 rs7867795 9 G/A 0.02 −21.81 1.48 × 10−7 6.13 3.41 × 10−6
TENT5A rs112141659 6 G/A 0.0317 −17.01 3.11 × 10−7 3.25 2.59 × 10−3
GALR1 rs144060810 18 T/C 0.0119 −27.17 3.27 × 10−7 8.33 6.55 × 10−7
LINC00478 rs238997 21 T/C 0.0158 −22.96 7.46 × 10−7 5.36 3.26 × 10−4

* p < 5 × 10−8, genome-wide significant association; MAF, minor allele frequency; beta refers to the A1 allele.