Table 1.

Sliding clamp-binding proteins. Table shows the list of various cellular processes and the proteins that interact with the sliding clamp during these processes.

Process	Proteins Interacting with Eukaryotic PCNA	Proteins Interacting with Bacterial Sliding Clamp
DNA replication	DNA Polymerase δ, DNA Polymerase ε, Replication factor (RfC1, Rfc3, Rfc4), Flap endonuclease (FEN-1), DNA ligase 1, DNA topoisomerase 1, Cdt1, Topo Iiα	DNA Polymerase III, DnaA, Clamp loader complex, DNA Polymerase I, DNA ligase
DNA repair	DNA mismatch repair protein Msh3, Msh6, Mlh1, Exonuclease 1, UNG2, MPG, PARP-1, APE1, APE2, XRCC1, WRN, BLM, RECQ5, NTH1, hMYH, XPG	MutL, MutS, NucS, Nei2, XthA, DNA Polymerase IV, DNA Polymerase V
DNA damage	DNA Polymerase η, DNA Polymerase ζ, DNA Polymerase λ, DNA Polymerase κ, DNA repair protein REV1, E3 ubiquitin-protein ligase RAD18 and Rad5
Chromatin Assembly	WSTF, DNMT1, HDAC1, p300, CAF-1	_
Cell cycle control	p21 (C1P1/WAF1), P27 (KIP2), Cyclin D1, MCL1, P15 (PAF), CDK2, ING1b, Gadd45, MyD118, CR6, P53, MDM2	DnaA, Hda
Sister chromatid cohesion	ESCO1, ESCO2, Chl1, Ctf18	_