Table 1.
Modifications of POLDIP3.
| Position | Sequence | Kinase/Enzyme | References | |
|---|---|---|---|---|
| Phosphorylation | S42 | QQGLLS*QSTRTA | ATM/ATR; Chk1 | 14 and 40 |
| S63 | QKIGLS*DARLK | Chk1 | 40 | |
| S127 | SLKRSS*PAAFI | 6 | ||
| S275 | AEPVLS*PLEGT | 6 | ||
| S383/S385 | PRRVNS*AS*SSNPP | S6K1 | 6 | |
| S405/S406 | KALFKS*S*GASV | 6 | ||
| Sumoylation | K59 | FDARQK*IGLSD | 15 | |
| K68 | SDARLK*LGVKD | 15 | ||
| K72 | LKLGVK*DAREK | 15 | ||
| K102 | MLNSRK*QQTTV | 15 | ||
| K144 | VTPALK*LTKTI | 15 | ||
| K147 | ALKLTK*TIQVP | 15 | ||
| K155 | QVPQQK*AMAPL | 15 | ||
| K178 | NNHQAK*QNLYD | 15 | ||
| K197 | ASVPTK*QMKFA | 15 | ||
| K200 | PTKQMK*FAASG | 15 | ||
| K223 | KLSMSK*ALPLT | 15 | ||
| K248 | SSIRTK*ALTNM | 15 | ||
| K260 | RTLVNK*EEPPK | 15 | ||
| K281 | PLEGTK*MTVNN | 15 | ||
| K323 | EVVFVK*KDDAI | 15 | ||
| K333 | ITAYKK*YNNRC | 16 | ||
| K372 | DSPSMK*KESEL | 15 and 16 | ||
| K400 | PDTILK*ALFKS | 15 | ||
| K418 | QPTEFK*IKL | 15 |
Notes: * mark the sites of modifications. The bolded and underlined letters mark the SUMO consensus sequences.