Table 5.
Comparison of MS between the four subgroups: case group with alternate allele, case group with wild-type allele, control group with alternate allele, and control group with wild-type allele.
| Case Group | Control Group | |||||
|---|---|---|---|---|---|---|
| Gene | SNV | MS Alternate Allele | MS Wild-Type | MS Alternate Allele | MS Wild-Type | p |
| AXIN1 | rs370681 | 71.98 (SD: ±35.66) | 75. 64 (SD: ±37.19) | 98.19 (SD: ±49.09) | 94.81 (SD: ±28.77) | 0.651 |
| rs12921862 | 74.95 (SD: ±35.26) | 66.58 (SD: ±21.52) | 70.26 (SD: ±27.03) | 101 (SD: ±41.64) | 0.093 | |
| rs1805105 | 74.09 (SD: ±34.78) | 73.47 (SD: ±38.46) | 99.015 (SD: ±44.78) | 92.1 (SD: ±29.98) | 0.574 | |
| TBX20 | rs4720169 | 5.23 (SD: ±7.99) | 2.37 (SD: ±0.43) | 10.46 (SD: ±22.41) | 12.10 (SD: ±21.71) | 0.354 |
| TBX1 | rs41260844 | 5.97 (SD: ±4.1) | 3.88 (SD: ±5.97) | 4.84 (SD: ±7.2) | 6.2 (SD: ±12.53) | 0.064 |
| MTHFR | rs1801133 | 4.85 (SD: ±6.63) | 4.34 (SD: ±4.90) | 37.34 (SD: ±85.9) | 3.245 (SD: ±8.8) | 0.004 |
| rs1801131 | 4.48 (SD: ±5.88) | 4.46 (SD: ±2.68) | 10.89 (SD: ±43.18) | 4.52 (SD: ±4.76) | 0.007 | |
MS—methylation status. Statistically significant difference: p < 0.0471 by Bonferroni inequalities.