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. 2022 Nov 18;13(11):2152. doi: 10.3390/genes13112152

Figure 3.

Figure 3

Targeted regulation of Gab2 by hsa-miR-9 and hsa-miR-181a. (A) Gab2 binding sites in hsa-miR-9 and hsa-miR-181a predicted by bioinformatics websites. (B) miRNAs with mutation of the Gab2 3′UTR binding site. (C,D) Analysis of the interaction between Gab2 and hsa-miR-9 (C) or hsa-miR-181a (D) by a dual-luciferase assay. The results are presented as the means ± SDs. Statistical comparisons of values were made using Student’s t-test. Red boxs indicate the mutated sequences. ns, nonsignificant; * p < 0.05.