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. 2022 Nov 8;23(22):13686. doi: 10.3390/ijms232213686
AS-PCR allele-specific oligonucleotide polymerase chain reaction
ASCT autologous stem cell transplant
BM bone marrow
CAR-T cells chimeric antigen receptor-T cells
CHUSJ Centro Hospitalar Universitário São João
cfDNA cell-free DNA
CTCs circulating tumor cells
ctDNA circulating tumor DNA
CR complete response
D100 day 100 after ASCT
ECL enhanced chemiluminescence
EMD extramedullary disease
EVs Extracellular Vesicles
FDG-PET/CT 18-fluoro-2-deoxyglucos positron emission tomography/computed tomography
FISH Fluorescence in situ hybridization
FPM Fuji Medical Film Processor
Ig immunoglobulin
IMWG International Myeloma Working Group
ISS International Staging System
K immunoglobulin kappa (κ) chain
L immunoglobulin lambda (λ) chain
LOD limit of detection
MFC multiparameter flow cytometry
MM Multiple Myeloma
MRD measurable residual disease
MSCs BM mesenchymal stem cells
MW molecular weight
NGF next-generation flow
NGS next-generation sequencing
NTA Nanoparticle Tracking Analysis
OS overall survival
PB peripheral blood
PBS phosphate-buffered saline
PC plasma cells
PFS progression free-survival
PPP Platelet-Poor Plasma
PRP Platelet-Rich Plasma
R-ISS revised-ISS
RT room temperature
sCR stringent complete response
SEC Size Exclusion Chromatography
TBS-T Tris-buffered saline solution with 0.1% Tween-20
TEM Transmission Electron Microscopy
UF ultrafiltration
UF ultrafiltrated pool from SEC fractions 3 to 6
VEGF vascular endothelial growth factor
VGPR very good partial response
WB Western Blot