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. 2022 Nov 8;23(22):13706. doi: 10.3390/ijms232213706

Figure 1.

Figure 1

Effect of SPD-FSAP on histones-induced permeability. (A) Histones (50 µg/mL) induced the permeability of both HUVECs and HAoECs. Permeability ratio was calculated as the rate relative to control. Data are presented as mean ± SEM; n = 3, *** p < 0.001. (B) WT–SPD–FSAP (10 µg/mL) had no effect on the permeability of HUVECs. (C) 0.1, 1, and 10 µg/mL WT–SPD–FSAP repressed the increased permeability induced by 50 µg/mL histones, while 10 µg/mL MI–SPD–FSAP had no effect. Data are presented as mean ± SEM; n = 3, * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. N represents 3 independent experiments, with 3 replicates in each experiment.