Table 2.
Adults with 22q11.2DS (n = 368) comparing those with (n = 51) and without (n = 317) liveborn offspring.
| Demographic/Clinical Variables | Live Offspring (n = 51) |
No Live Offspring (n = 317) 1 |
Chi-Square/Wilcoxon Two-Sample Test | |
|---|---|---|---|---|
| n (%) | n (%) | χ2 | p-Value | |
| Mild intellectual disability | 13 (25.5) | 181 (57.1) | 16.36 | <0.0001 |
| Male sex | 12 (23.5) | 161 (50.8) | 12.03 | 0.0005 |
| Psychotic illness | 7 (13.7) | 116 (36.6) | 9.32 | 0.0023 |
| Major congenital heart disease | 11 (21.6) | 110 (34.7) | 2.86 | 0.0906 |
| Median (Range) | Z | |||
| Current age | 45.8 (24.7–76.3) | 30.5 (17.9–67.6) | 6.94 | <0.0001 |
1 Includes n = 12 individuals with a history of pregnancy. Bold font indicates statistically significant findings.