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. 2022 Sep 13;11:e78717. doi: 10.7554/eLife.78717

Table 2. Overlap in significantly activated voxels at the individual and group level across both time points for CS discrimination.

Level Phase Coeff. ROI
Whole brain Insula Amygdala Hippocampus Caudate Putamen Pallidum Accumbens Thalamus dACC dlPFC vmPFC
(A) Individual Acq Jaccard 0.076 0.075 0.011 0.012 0.039 0.037 0.018 0.017 0.033 0.132 0.080 0.039
Dice 0.131 0.121 0.018 0.021 0.057 0.058 0.029 0.024 0.055 0.189 0.118 0.061
Ext Jaccard 0.007 0.001 0.000 0.000 0.001 0.000 0.000 0.000 0.001 0.003 0.001 0.005
Dice 0.014 0.001 0.000 0.000 0.001 0.000 0.000 0.001 0.001 0.006 0.002 0.009
(B) Group Acq Jaccard 0.620 0.595 0.294 0.323 0.613 0.740 0.747 0.441 0.834 0.898 0.895 0.045
Dice 0.765 0.745 0.448 0.472 0.760 0.847 0.855 0.595 0.910 0.946 0.944 0.086
Ext Jaccard 0.057 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.044 0.014 0.000
Dice 0.108 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.085 0.028 0.000

Note. Results are shown for the whole brain as well as for selected regions of interest (ROIs) for fear acquisition training and extinction training. Both coefficients range from 0 (no overlap) to 1 (perfect overlap). Note that the Jaccard can be interpreted as % (Maitra, 2010). NAcc = nucleus accumbens; dACC = dorsal anterior cingulate cortex; dlPFC = dorsolateral prefrontal cortex; vmPFC = ventromedial prefrontal cortex.