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. 2022 Nov 10;19(22):14812. doi: 10.3390/ijerph192214812

Table 1.

Details of selected drug targets.

Proteins Subcellular Localization Transmembrane Helices Molecular Weight Stability Molecular Function Biological Processes
Ferric iron uptake transcriptional regulator (FUR) Cytoplasm 0 16,765.81 Stable DNA-binding transcription factor activity regulation of transcription, DNA-templated
UDP-2,3diacylglucosamine diphosphatase
(UDP)
Cytoplasm 0 26,832.02 Stable pyrophosphatase activity
hydrolase activity
lipid A biosynthetic process
lipid-A-disaccharide synthase
(lpxB)
Cytoplasm 0 42,472.56 Stable lipid-A-disaccharide synthase activity lipid A biosynthetic process